Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors

Neuroblastoma is a pediatric tumor characterized by histologic heterogeneity, and accounts for ~15% of childhood deaths from cancer. The five-year survival for patients with high-risk stage 4 disease has not improved in two decades. We used whole exome sequencing (WES) to identify mutations present...

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Detalles Bibliográficos
Autores principales: Miller, Aubrey L., Garcia, Patrick L., Pressey, Joseph G., Beierle, Elizabeth A., Kelly, David R., Crossman, David K., Council, Leona N., Daniel, Richard, Watts, Raymond G., Cramer, Stuart L., Yoon, Karina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736554/
https://www.ncbi.nlm.nih.gov/pubmed/29259192
http://dx.doi.org/10.1038/s41598-017-17162-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736554/
https://www.ncbi.nlm.nih.gov/pubmed/29259192
http://dx.doi.org/10.1038/s41598-017-17162-y

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