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Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors
Neuroblastoma is a pediatric tumor characterized by histologic heterogeneity, and accounts for ~15% of childhood deaths from cancer. The five-year survival for patients with high-risk stage 4 disease has not improved in two decades. We used whole exome sequencing (WES) to identify mutations present...
Autores principales: | Miller, Aubrey L., Garcia, Patrick L., Pressey, Joseph G., Beierle, Elizabeth A., Kelly, David R., Crossman, David K., Council, Leona N., Daniel, Richard, Watts, Raymond G., Cramer, Stuart L., Yoon, Karina J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736554/ https://www.ncbi.nlm.nih.gov/pubmed/29259192 http://dx.doi.org/10.1038/s41598-017-17162-y |
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