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Clinical Implications of the Autophagy Core Gene Variations in Advanced Lung Adenocarcinoma Treated with Gefitinib

EGFR-TKIs show dramatic treatment benefits for advanced lung adenocarcinoma patients with activating EGFR mutations. Considering the essential role of autophagy in EGFR-TKIs treatments, we hypothesized that genetic variants in autophagy core genes might contribute to outcomes of advanced lung adenoc...

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Detalles Bibliográficos
Autores principales: Yuan, Jupeng, Zhang, Nasha, Yin, Longbin, Zhu, Hui, Zhang, Li, Zhou, Liqing, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736620/
https://www.ncbi.nlm.nih.gov/pubmed/29259263
http://dx.doi.org/10.1038/s41598-017-18165-5