Catastrophic disassembly of actin filaments via Mical-mediated oxidation

Actin filament assembly and disassembly are vital for cell functions. MICAL Redox enzymes are important post-translational effectors of actin that stereo-specifically oxidize actin’s M44 and M47 residues to induce cellular F-actin disassembly. Here we show that Mical-oxidized (Mox) actin can undergo...

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Detalles Bibliográficos
Autores principales: Grintsevich, Elena E., Ge, Peng, Sawaya, Michael R., Yesilyurt, Hunkar Gizem, Terman, Jonathan R., Zhou, Z. Hong, Reisler, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736627/
https://www.ncbi.nlm.nih.gov/pubmed/29259197
http://dx.doi.org/10.1038/s41467-017-02357-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736627/
https://www.ncbi.nlm.nih.gov/pubmed/29259197
http://dx.doi.org/10.1038/s41467-017-02357-8

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