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Beneficial mutation-selection dynamics in finite asexual populations: a free boundary approach
Using a free boundary approach based on an analogy with ice melting models, we propose a deterministic PDE framework to describe the dynamics of fitness distributions in the presence of beneficial mutations with non-epistatic effects on fitness. Contrarily to most approaches based on deterministic m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736637/ https://www.ncbi.nlm.nih.gov/pubmed/29259180 http://dx.doi.org/10.1038/s41598-017-17212-5 |