Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation

Human mitochondrial transcription factor A (TFAM) has been implicated in promoting tumor growth and invasion. TFAM activates mitochondrial DNA (mtDNA) transcription, and affects nuclear gene expression through mitochondrial retrograde signaling. In this study, we investigated the effects of TFAM dep...

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Detalles Bibliográficos
Autores principales: Lee, Woo Rin, Na, Heeju, Lee, Seon Woo, Lim, Won-Jun, Kim, Namshin, Lee, J. Eugene, Kang, Changwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736646/
https://www.ncbi.nlm.nih.gov/pubmed/29259235
http://dx.doi.org/10.1038/s41598-017-18064-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736646/
https://www.ncbi.nlm.nih.gov/pubmed/29259235
http://dx.doi.org/10.1038/s41598-017-18064-9

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