Cargando…
Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation
Human mitochondrial transcription factor A (TFAM) has been implicated in promoting tumor growth and invasion. TFAM activates mitochondrial DNA (mtDNA) transcription, and affects nuclear gene expression through mitochondrial retrograde signaling. In this study, we investigated the effects of TFAM dep...
Autores principales: | Lee, Woo Rin, Na, Heeju, Lee, Seon Woo, Lim, Won-Jun, Kim, Namshin, Lee, J. Eugene, Kang, Changwon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736646/ https://www.ncbi.nlm.nih.gov/pubmed/29259235 http://dx.doi.org/10.1038/s41598-017-18064-9 |
Ejemplares similares
-
Mitochondrial DNA depletion, mitochondrial mutations and high TFAM expression in hepatocellular carcinoma
por: Qiao, Lihua, et al.
Publicado: (2017) -
Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response
por: Qi, Yan, et al.
Publicado: (2022) -
A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM)
por: Choi, Woo Suk, et al.
Publicado: (2021) -
Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM
por: Lan, Linhua, et al.
Publicado: (2017) -
Genome-Wide Analysis Reveals Coating of the Mitochondrial Genome by TFAM
por: Wang, Yun E., et al.
Publicado: (2013)