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AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis

Over 1.5 million individuals suffer from cornea vascularization due to genetic and/or environmental factors, compromising visual acuity and often resulting in blindness. Current treatments of corneal vascularization are limited in efficacy and elicit undesirable effects including, ironically, vision...

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Detalles Bibliográficos
Autores principales: Hirsch, Matthew L., Conatser, Laura M., Smith, Sara M., Salmon, Jacklyn H., Wu, Jerry, Buglak, Nicholas E., Davis, Rich, Gilger, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736662/
https://www.ncbi.nlm.nih.gov/pubmed/29259248
http://dx.doi.org/10.1038/s41598-017-18002-9