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AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis
Over 1.5 million individuals suffer from cornea vascularization due to genetic and/or environmental factors, compromising visual acuity and often resulting in blindness. Current treatments of corneal vascularization are limited in efficacy and elicit undesirable effects including, ironically, vision...
Autores principales: | Hirsch, Matthew L., Conatser, Laura M., Smith, Sara M., Salmon, Jacklyn H., Wu, Jerry, Buglak, Nicholas E., Davis, Rich, Gilger, Brian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736662/ https://www.ncbi.nlm.nih.gov/pubmed/29259248 http://dx.doi.org/10.1038/s41598-017-18002-9 |
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