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VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways

The ability to control vascular endothelial growth factor (VEGF) signaling offers promising therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted therapies are not clinically effective for many pathologies, such as breast cancer. VEGFR1 has recently emerged as a...

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Detalles Bibliográficos
Autores principales: Weddell, Jared C., Chen, Si, Imoukhuede, P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736688/
https://www.ncbi.nlm.nih.gov/pubmed/29263797
http://dx.doi.org/10.1038/s41540-017-0037-9