Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including the matrix degradation enzyme matrix metalloproteinases 9 (MMP9) and the EMT transcription f...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Wen-Sheng, You, Ren-In, Cheng, Chuan-Chu, Lee, Ming-Che, Lin, Teng-Yi, Hu, Chi-Tan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736704/
https://www.ncbi.nlm.nih.gov/pubmed/29259250
http://dx.doi.org/10.1038/s41598-017-18101-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736704/
https://www.ncbi.nlm.nih.gov/pubmed/29259250
http://dx.doi.org/10.1038/s41598-017-18101-7

Ejemplares similares