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Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1
The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including the matrix degradation enzyme matrix metalloproteinases 9 (MMP9) and the EMT transcription f...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736704/ https://www.ncbi.nlm.nih.gov/pubmed/29259250 http://dx.doi.org/10.1038/s41598-017-18101-7 |