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Single-Particle Discrimination of Retroviruses from Extracellular Vesicles by Nanoscale Flow Cytometry
Retroviruses and small EVs overlap in size, buoyant densities, refractive indices and share many cell-derived surface markers making them virtually indistinguishable by standard biochemical methods. This poses a significant challenge when purifying retroviruses for downstream analyses or for phenoty...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736735/ https://www.ncbi.nlm.nih.gov/pubmed/29259315 http://dx.doi.org/10.1038/s41598-017-18227-8 |