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Single-Particle Discrimination of Retroviruses from Extracellular Vesicles by Nanoscale Flow Cytometry

Retroviruses and small EVs overlap in size, buoyant densities, refractive indices and share many cell-derived surface markers making them virtually indistinguishable by standard biochemical methods. This poses a significant challenge when purifying retroviruses for downstream analyses or for phenoty...

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Detalles Bibliográficos
Autores principales: Tang, Vera A., Renner, Tyler M., Fritzsche, Anna K., Burger, Dylan, Langlois, Marc-André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736735/
https://www.ncbi.nlm.nih.gov/pubmed/29259315
http://dx.doi.org/10.1038/s41598-017-18227-8