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Promoter methylation of cysteine dioxygenase type 1: gene silencing and tumorigenesis in hepatocellular carcinoma

BACKGROUNDS/AIMS: Cysteine dioxygenase type 1 (CDO1) acts as a tumor suppressor and is silenced by promoter methylation in various malignancies. The relationship between the CDO1 methylation status and hepatocellular carcinoma (HCC) tumorigenesis was evaluated. METHODS: Using a HCC cell line (SNU423...

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Detalles Bibliográficos
Autores principales: Choi, Jung-il, Cho, Eung-Ho, Kim, Sang Bum, Kim, Ryounggo, Kwon, Junhye, Park, Misun, Shin, Hye-Jin, Ryu, Han Suk, Park, Sun-Hoo, Lee, Kee-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736736/
https://www.ncbi.nlm.nih.gov/pubmed/29264579
http://dx.doi.org/10.14701/ahbps.2017.21.4.181