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Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue

PURPOSE: Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers. METHODS: Anionic PAM...

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Detalles Bibliográficos
Autores principales: Morris, Christopher J., Aljayyoussi, Ghaith, Mansour, Omar, Griffiths, Peter, Gumbleton, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736778/
https://www.ncbi.nlm.nih.gov/pubmed/28616685
http://dx.doi.org/10.1007/s11095-017-2190-7