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Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue
PURPOSE: Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers. METHODS: Anionic PAM...
Autores principales: | Morris, Christopher J., Aljayyoussi, Ghaith, Mansour, Omar, Griffiths, Peter, Gumbleton, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736778/ https://www.ncbi.nlm.nih.gov/pubmed/28616685 http://dx.doi.org/10.1007/s11095-017-2190-7 |
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