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Mapping Extracellular pH of Gliomas in Presence of Superparamagnetic Nanoparticles: Towards Imaging the Distribution of Drug-Containing Nanoparticles and Their Curative Effect on the Tumor Microenvironment

Since brain's microvasculature is compromised in gliomas, intravenous injection of tumor-targeting nanoparticles containing drugs (D-NPs) and superparamagnetic iron oxide (SPIO-NPs) can deliver high payloads of drugs while allowing MRI to track drug distribution. However, therapeutic effect of...

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Detalles Bibliográficos
Autores principales: Maritim, Samuel, Coman, Daniel, Huang, Yuegao, Rao, Jyotsna U., Walsh, John J., Hyder, Fahmeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736903/
https://www.ncbi.nlm.nih.gov/pubmed/29362558
http://dx.doi.org/10.1155/2017/3849373