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Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable Haemophilus influenzae

Biofilms formed in the middle ear by nontypeable Haemophilus influenzae (NTHI) are central to the chronicity, recurrence, and refractive nature of otitis media (OM). However, mechanisms that underlie the emergence of specific NTHI biofilm structures are unclear. We combined computational analysis to...

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Detalles Bibliográficos
Autores principales: Das, Jayajit, Mokrzan, Elaine, Lakhani, Vinal, Rosas, Lucia, Jurcisek, Joseph A., Ray, William C., Bakaletz, Lauren O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736908/
https://www.ncbi.nlm.nih.gov/pubmed/29259083
http://dx.doi.org/10.1128/mBio.01466-17