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Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter

Borrelia burgdorferi is an extreme amino acid (AA) auxotroph whose genome encodes few free AA transporters and an elaborate oligopeptide transport system (B. burgdorferi Opp [BbOpp]). BbOpp consists of five oligopeptide-binding proteins (OBPs), two heterodimeric permeases, and a heterodimeric nucleo...

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Detalles Bibliográficos
Autores principales: Groshong, Ashley M., Dey, Abhishek, Bezsonova, Irina, Caimano, Melissa J., Radolf, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736914/
https://www.ncbi.nlm.nih.gov/pubmed/29259089
http://dx.doi.org/10.1128/mBio.02047-17