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SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells

Cystic fibrosis (CF) is caused by mutations in the CFTR gene and is associated with progressive and ultimately fatal infectious lung disease. There can be considerable variability in disease severity among individuals with the same CFTR mutations, and recent genome-wide association studies have iden...

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Detalles Bibliográficos
Autores principales: Di Paola, Michelle, Park, Amber J., Ahmadi, Saumel, Roach, Elyse J., Wu, Yu-Sheng, Struder-Kypke, Michaela, Lam, Joseph S., Bear, Christine E., Khursigara, Cezar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736915/
https://www.ncbi.nlm.nih.gov/pubmed/29259090
http://dx.doi.org/10.1128/mBio.02073-17