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Long-Term High Salt Intake Involves Reduced SK Currents and Increased Excitability of PVN Neurons with Projections to the Rostral Ventrolateral Medulla in Rats

Evidence indicates that high salt (HS) intake activates presympathetic paraventricular nucleus (PVN) neurons, which contributes to sympathoexcitation of salt-sensitive hypertension. The present study determined whether 5 weeks of HS (2% NaCl) intake alters the small conductance Ca(2+)-activated pota...

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Detalles Bibliográficos
Autores principales: Chapp, Andrew D., Wang, Renjun, Cheng, Zixi (Jack), Shan, Zhiying, Chen, Qing-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736939/
https://www.ncbi.nlm.nih.gov/pubmed/29362678
http://dx.doi.org/10.1155/2017/7282834