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SLE and Serum Complement: Causative, Concomitant or Coincidental?

BACKGROUND: Systemic Lupus Erythematosus (SLE) is an incurable autoimmune disorder with complement activation playing a key role in the pathogenesis of immune-mediated tissue injury. While quantifying complement to monitor SLE disease activity has been the standard of care since the 1950s, decreased...

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Detalles Bibliográficos
Autores principales: Sandhu, Vaneet, Quan, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737025/
https://www.ncbi.nlm.nih.gov/pubmed/29290848
http://dx.doi.org/10.2174/1874312901711010113