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Mechanism of opening a sliding clamp

Clamp loaders load ring-shaped sliding clamps onto DNA where the clamps serve as processivity factors for DNA polymerases. In the first stage of clamp loading, clamp loaders bind and stabilize clamps in an open conformation, and in the second stage, clamp loaders place the open clamps around DNA so...

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Detalles Bibliográficos
Autores principales: Douma, Lauren G., Yu, Kevin K., England, Jennifer K., Levitus, Marcia, Bloom, Linda B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737080/
https://www.ncbi.nlm.nih.gov/pubmed/28973453
http://dx.doi.org/10.1093/nar/gkx665