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Mechanism of opening a sliding clamp
Clamp loaders load ring-shaped sliding clamps onto DNA where the clamps serve as processivity factors for DNA polymerases. In the first stage of clamp loading, clamp loaders bind and stabilize clamps in an open conformation, and in the second stage, clamp loaders place the open clamps around DNA so...
Autores principales: | Douma, Lauren G., Yu, Kevin K., England, Jennifer K., Levitus, Marcia, Bloom, Linda B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737080/ https://www.ncbi.nlm.nih.gov/pubmed/28973453 http://dx.doi.org/10.1093/nar/gkx665 |
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