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Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality

Biologically functional DNA hairpins are found in archaea, prokaryotes and eukaryotes, playing essential roles in various DNA transactions. However, during DNA replication, hairpin formation can stall the polymerase and is therefore prevented by the single-stranded DNA binding protein (SSB). Here, w...

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Detalles Bibliográficos
Autores principales: Grieb, Maj Svea, Nivina, Aleksandra, Cheeseman, Bevan L., Hartmann, Andreas, Mazel, Didier, Schlierf, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737091/
https://www.ncbi.nlm.nih.gov/pubmed/28985409
http://dx.doi.org/10.1093/nar/gkx670