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Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences
The emergence of catalytic RNA is believed to have been a key event during the origin of life. Understanding how catalytic activity is distributed across random sequences is fundamental to estimating the probability that catalytic sequences would emerge. Here, we analyze the in vitro evolution of tr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737207/ https://www.ncbi.nlm.nih.gov/pubmed/28645146 http://dx.doi.org/10.1093/nar/gkx540 |