Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences

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The emergence of catalytic RNA is believed to have been a key event during the origin of life. Understanding how catalytic activity is distributed across random sequences is fundamental to estimating the probability that catalytic sequences would emerge. Here, we analyze the in vitro evolution of tr...

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Detalles Bibliográficos
Autores principales: Pressman, Abe, Moretti, Janina E., Campbell, Gregory W., Müller, Ulrich F., Chen, Irene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737207/
https://www.ncbi.nlm.nih.gov/pubmed/28645146
http://dx.doi.org/10.1093/nar/gkx540
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