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A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans
Candida albicans is an important opportunistic fungal pathogen capable of causing both mucosal and disseminated disease. Infections are often treated with fluconazole, a front-line antifungal drug that targets the biosynthesis of ergosterol, a major component of the fungal cell membrane. Resistance...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Microbiology Society
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737213/ https://www.ncbi.nlm.nih.gov/pubmed/28640746 http://dx.doi.org/10.1099/mic.0.000478 |