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Quantitative specificity of STAT1 and several variants

The quantitative specificity of the STAT1 transcription factor was determined by measuring the relative affinity to hundreds of variants of the consensus binding site including variations in the length of the site. The known consensus sequence is observed to have the highest affinity, with all varia...

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Detalles Bibliográficos
Autores principales: Roy, Basab, Zuo, Zheng, Stormo, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737217/
https://www.ncbi.nlm.nih.gov/pubmed/28510715
http://dx.doi.org/10.1093/nar/gkx393