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Initiating ribosomes and a 5′/3′-UTR interaction control ribonuclease action to tightly couple B. subtilis hbs mRNA stability with translation

We previously showed that ribosomes initiating translation of the B. subtilis hbs mRNA at a strong Shine–Dalgarno sequence block the 5′ exoribonuclease RNase J1 from degrading into the coding sequence. Here, we identify new and previously unsuspected features of this mRNA. First, we identify RNase Y...

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Detalles Bibliográficos
Autores principales: Braun, Frédérique, Durand, Sylvain, Condon, Ciarán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737220/
https://www.ncbi.nlm.nih.gov/pubmed/28977557
http://dx.doi.org/10.1093/nar/gkx793