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The double-stranded RNA binding protein RDE-4 can act cell autonomously during feeding RNAi in C. elegans

Long double-stranded RNA (dsRNA) can silence genes of matching sequence upon ingestion in many invertebrates and is therefore being developed as a pesticide. Such feeding RNA interference (RNAi) is best understood in the worm Caenorhabditis elegans, where the dsRNA-binding protein RDE-4 initiates si...

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Detalles Bibliográficos
Autores principales: Raman, Pravrutha, Zaghab, Soriayah M., Traver, Edward C., Jose, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737277/
https://www.ncbi.nlm.nih.gov/pubmed/28541563
http://dx.doi.org/10.1093/nar/gkx484