Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter

EGFR is an oncogene which codifies for a tyrosine kinase receptor that represents an important target for anticancer therapy. Indeed, several human cancers showed an upregulation of the activity of this protein. The promoter of this gene contains some G-rich domains, thus representing a yet unexplor...

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Detalles Bibliográficos
Autores principales: Greco, Maria L., Kotar, Anita, Rigo, Riccardo, Cristofari, Camilla, Plavec, Janez, Sissi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737278/
https://www.ncbi.nlm.nih.gov/pubmed/28973461
http://dx.doi.org/10.1093/nar/gkx678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737278/
https://www.ncbi.nlm.nih.gov/pubmed/28973461
http://dx.doi.org/10.1093/nar/gkx678

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