Dicer-independent processing of small RNA duplexes: mechanistic insights and applications

MicroRNAs (miRNAs) play a pivotal role in the regulation of cellular gene expression via the conserved RNA interference (RNAi) mechanism. Biogenesis of the unusual miR-451 does not require Dicer. This molecule is instead processed by the Argonaute 2 (Ago2) enzyme. Similarly, unconventional short hai...

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Detalles Bibliográficos
Autores principales: Herrera-Carrillo, Elena, Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737282/
https://www.ncbi.nlm.nih.gov/pubmed/28977573
http://dx.doi.org/10.1093/nar/gkx779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737282/
https://www.ncbi.nlm.nih.gov/pubmed/28977573
http://dx.doi.org/10.1093/nar/gkx779

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