Influence of nucleotide modifications at the C2’ position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA

Polyadenylate (poly(A)) has the ability to form a parallel duplex with Hoogsteen adenine:adenine base pairs at low pH or in the presence of ammonium ions. In order to evaluate the potential of this structural motif for nucleic acid-based nanodevices, we characterized the effects on duplex stability...

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Detalles Bibliográficos
Autores principales: Copp, William, Denisov, Alexey Y., Xie, Jingwei, Noronha, Anne M., Liczner, Christopher, Safaee, Nozhat, Wilds, Christopher J., Gehring, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737284/
https://www.ncbi.nlm.nih.gov/pubmed/28973475
http://dx.doi.org/10.1093/nar/gkx713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737284/
https://www.ncbi.nlm.nih.gov/pubmed/28973475
http://dx.doi.org/10.1093/nar/gkx713

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