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Influence of nucleotide modifications at the C2’ position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA
Polyadenylate (poly(A)) has the ability to form a parallel duplex with Hoogsteen adenine:adenine base pairs at low pH or in the presence of ammonium ions. In order to evaluate the potential of this structural motif for nucleic acid-based nanodevices, we characterized the effects on duplex stability...
Autores principales: | Copp, William, Denisov, Alexey Y., Xie, Jingwei, Noronha, Anne M., Liczner, Christopher, Safaee, Nozhat, Wilds, Christopher J., Gehring, Kalle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737284/ https://www.ncbi.nlm.nih.gov/pubmed/28973475 http://dx.doi.org/10.1093/nar/gkx713 |
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