Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells

Direct reprogramming can be achieved by forced expression of master transcription factors. Yet how such factors mediate repression of initial cell-type-specific genes while activating target cell-type-specific genes is unclear. Through embryonic stem (ES) to trophoblast stem (TS)-like cell reprogram...

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Detalles Bibliográficos
Autores principales: Rhee, Catherine, Lee, Bum-Kyu, Beck, Samuel, LeBlanc, Lucy, Tucker, Haley O., Kim, Jonghwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737334/
https://www.ncbi.nlm.nih.gov/pubmed/28973471
http://dx.doi.org/10.1093/nar/gkx692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737334/
https://www.ncbi.nlm.nih.gov/pubmed/28973471
http://dx.doi.org/10.1093/nar/gkx692

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