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Tandem phage-display for the identification of non-overlapping binding pairs of recombinant affinity reagents

The ‘sandwich’ binding format, which uses two reagents that can bind simultaneously to a given analyte, is the gold standard in diagnostics and many biochemical techniques. One of the bottlenecks in creating a sandwich assay is identifying pairs of reagents that bind non-competitively to the target....

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Detalles Bibliográficos
Autores principales: Gorman, Kevin T., Roby, Lauren C., Giuffre, Allison, Huang, Renhua, Kay, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737338/
https://www.ncbi.nlm.nih.gov/pubmed/28985360
http://dx.doi.org/10.1093/nar/gkx688