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Characterization of a coupled DNA replication and translesion synthesis polymerase supraholoenzyme from archaea

The ability of the replisome to seamlessly coordinate both high fidelity and translesion DNA synthesis requires a means to regulate recruitment and binding of enzymes from solution. Co-occupancy of multiple DNA polymerases within the replisome has been observed primarily in bacteria and is regulated...

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Detalles Bibliográficos
Autores principales: Cranford, Matthew T., Chu, Aurea M., Baguley, Joshua K., Bauer, Robert J., Trakselis, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737361/
https://www.ncbi.nlm.nih.gov/pubmed/28655184
http://dx.doi.org/10.1093/nar/gkx539