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Characterization of a coupled DNA replication and translesion synthesis polymerase supraholoenzyme from archaea
The ability of the replisome to seamlessly coordinate both high fidelity and translesion DNA synthesis requires a means to regulate recruitment and binding of enzymes from solution. Co-occupancy of multiple DNA polymerases within the replisome has been observed primarily in bacteria and is regulated...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737361/ https://www.ncbi.nlm.nih.gov/pubmed/28655184 http://dx.doi.org/10.1093/nar/gkx539 |