Pausing kinetics dominates strand-displacement polymerization by reverse transcriptase

Reverse transcriptase (RT) catalyzes the conversion of the viral RNA into an integration-competent double-stranded DNA, with a variety of enzymatic activities that include the ability to displace a non-template strand concomitantly with polymerization. Here, using high-resolution optical tweezers to...

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Detalles Bibliográficos
Autores principales: Malik, Omri, Khamis, Hadeel, Rudnizky, Sergei, Marx, Ailie, Kaplan, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737391/
https://www.ncbi.nlm.nih.gov/pubmed/28973474
http://dx.doi.org/10.1093/nar/gkx720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737391/
https://www.ncbi.nlm.nih.gov/pubmed/28973474
http://dx.doi.org/10.1093/nar/gkx720

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