Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication

Base lesions in DNA can stall the replication machinery or induce mutations if bypassed. Consequently, lesions must be repaired before replication or in a post-replicative process to maintain genomic stability. Base excision repair (BER) is the main pathway for repair of base lesions and is known to...

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Detalles Bibliográficos
Autores principales: Bjørås, Karine Ø., Sousa, Mirta M. L., Sharma, Animesh, Fonseca, Davi M., Søgaard, Caroline K., Bjørås, Magnar, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737410/
https://www.ncbi.nlm.nih.gov/pubmed/28575236
http://dx.doi.org/10.1093/nar/gkx476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737410/
https://www.ncbi.nlm.nih.gov/pubmed/28575236
http://dx.doi.org/10.1093/nar/gkx476

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