Crowding-induced transcriptional bursts dictate polymerase and nucleosome density profiles along genes

During eukaryotic transcription, RNA polymerase (RNAP) translocates along DNA molecules covered with nucleosomes and other DNA binding proteins. Though the interactions between a single nucleosome and RNAP are by now fairly well understood, this understanding has not been synthesized into a descript...

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Detalles Bibliográficos
Autores principales: van den Berg, Aafke A., Depken, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737439/
https://www.ncbi.nlm.nih.gov/pubmed/28586463
http://dx.doi.org/10.1093/nar/gkx513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737439/
https://www.ncbi.nlm.nih.gov/pubmed/28586463
http://dx.doi.org/10.1093/nar/gkx513

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