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FASTmiR: an RNA-based sensor for in vitro quantification and live-cell localization of small RNAs

Small RNAs, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), play a variety of important regulatory roles in many eukaryotes. Their small size has made it challenging to study them directly in live cells. Here we describe an RNA-based fluorescent sensor for small RNA detection both...

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Detalles Bibliográficos
Autores principales: Huang, Kun, Doyle, Francis, Wurz, Zachary E., Tenenbaum, Scott A., Hammond, Reza K., Caplan, Jeffrey L., Meyers, Blake C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737440/
https://www.ncbi.nlm.nih.gov/pubmed/28586459
http://dx.doi.org/10.1093/nar/gkx504