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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis
Whereas ribosomes efficiently catalyze peptide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synthesis. Previous studies have shown that the translation factor eIF5A and its bacterial ortholog EF-P bind in the E site of the ribosome where they contact the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737446/ https://www.ncbi.nlm.nih.gov/pubmed/28637321 http://dx.doi.org/10.1093/nar/gkx532 |