Synchronized switching of multiple toxin–antitoxin modules by (p)ppGpp fluctuation

Toxin–antitoxin (TA) loci are widespread in bacteria including important pathogenic species. Recent studies suggest that TA systems play a key role in persister formation. However, the persistence phenotype shows only weak dependence on the number of TA systems, i.e. they are functionally redundant....

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Detalles Bibliográficos
Autores principales: Tian, Chengzhe, Semsey, Szabolcs, Mitarai, Namiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737467/
https://www.ncbi.nlm.nih.gov/pubmed/28854732
http://dx.doi.org/10.1093/nar/gkx552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737467/
https://www.ncbi.nlm.nih.gov/pubmed/28854732
http://dx.doi.org/10.1093/nar/gkx552

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