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Synchronized switching of multiple toxin–antitoxin modules by (p)ppGpp fluctuation
Toxin–antitoxin (TA) loci are widespread in bacteria including important pathogenic species. Recent studies suggest that TA systems play a key role in persister formation. However, the persistence phenotype shows only weak dependence on the number of TA systems, i.e. they are functionally redundant....
Autores principales: | Tian, Chengzhe, Semsey, Szabolcs, Mitarai, Namiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737467/ https://www.ncbi.nlm.nih.gov/pubmed/28854732 http://dx.doi.org/10.1093/nar/gkx552 |
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