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Acute Morphine Exposure Increases the Brain Distribution of [(18)F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates
BACKGROUND: The neuroinflammatory response to morphine exposure modulates its antinociceptive effects, tolerance, and dependence. Positron emission tomography radioligands for translocator protein-18kDa such as [(18)F]DPA-714 are noninvasive biomarkers of glial activation, a hallmark of neuroinflamm...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737475/ https://www.ncbi.nlm.nih.gov/pubmed/27581167 http://dx.doi.org/10.1093/ijnp/pyw077 |