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Acute Morphine Exposure Increases the Brain Distribution of [(18)F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates

BACKGROUND: The neuroinflammatory response to morphine exposure modulates its antinociceptive effects, tolerance, and dependence. Positron emission tomography radioligands for translocator protein-18kDa such as [(18)F]DPA-714 are noninvasive biomarkers of glial activation, a hallmark of neuroinflamm...

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Detalles Bibliográficos
Autores principales:	Auvity, Sylvain, Saba, Wadad, Goutal, Sébastien, Leroy, Claire, Buvat, Irène, Cayla, Jérôme, Caillé, Fabien, Bottlaender, Michel, Cisternino, Salvatore, Tournier, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737475/ https://www.ncbi.nlm.nih.gov/pubmed/27581167 http://dx.doi.org/10.1093/ijnp/pyw077

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