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Cell-to-cell variability and robustness in S-phase duration from genome replication kinetics

Genome replication, a key process for a cell, relies on stochastic initiation by replication origins, causing a variability of replication timing from cell to cell. While stochastic models of eukaryotic replication are widely available, the link between the key parameters and overall replication tim...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Bassetti, Federico, Gherardi, Marco, Lagomarsino, Marco Cosentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737480/
https://www.ncbi.nlm.nih.gov/pubmed/28854733
http://dx.doi.org/10.1093/nar/gkx556