Cargando…

Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break

Here, we use ChAP-MS (chromatin affinity purification with mass spectrometry), for the affinity purification of a sequence-specific single-copy endogenous chromosomal locus containing a DNA double-strand break (DSB). We found multiple new histone post-translational modifications enriched on chromati...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Pingping, Byrum, Stephanie, Fowler, Faith C., Pal, Sangita, Tackett, Alan J., Tyler, Jessica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737490/
https://www.ncbi.nlm.nih.gov/pubmed/29036368
http://dx.doi.org/10.1093/nar/gkx844