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Prioritizing tests of epistasis through hierarchical representation of genomic redundancies

Epistasis is defined as a statistical interaction between two or more genomic loci in terms of their association with a phenotype of interest. Epistatic loci that are identified using data from Genome-Wide Association Studies (GWAS) provide insights into the interplay among multiple genetic factors,...

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Detalles Bibliográficos
Autores principales: Cowman, Tyler, Koyutürk, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737499/
https://www.ncbi.nlm.nih.gov/pubmed/28605458
http://dx.doi.org/10.1093/nar/gkx505